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Prelims 2025 · Q48 · Biotechnology & genetics

With reference to monoclonal antibodies, often mentioned in news, consider the following statements :

  1. I.They are man-made proteins.
  2. II.They stimulate immunological function due to their ability to bind to specific antigens.
  3. III.They are used in treating viral infections like that of Nipah virus.

Which of the statements given above are correct?

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Answer: D. Statement I is correct: monoclonal antibodies are lab-made proteins that copy natural antibodies. Statement II is correct: they bind to a specific antigen and help the immune system act against it. Statement III is correct: monoclonal antibodies are used against viral infections; for Nipah, the antibody m102.4 has been given on compassionate grounds abroad, and ICMR procured it from Australia during the Kerala outbreaks (2018, 2023). Others are used for COVID-19 and RSV. So all three are correct.

Watch for: Students may think antibodies are used only for cancer or autoimmune disease and miss their use in viral infections like Nipah.

Why the other options are wrong
  • A. Wrong: Statement III is also correct.
  • B. Wrong: Statement I is also correct.
  • C. Wrong: Statement II is also correct.

Source to check: WHO Nipah virus fact sheet; news reports of September 2023 on ICMR procuring m102.4 doses from Australia

Answer from the official UPSC key. Written and fact-checked by AI against the official key. Spotted a mistake? Report it.